2026 March Madness bracket: Sweet 16 picks, NCAA Tournament predictions from elite college basketball expert

The 2026 NCAA Tournament has reached the Sweet 16 stage, with several teams vying for a spot in the Final Four. SportsLine expert Thomas Casale has made his predictions for the Sweet 16, including a major upset that could shake up the bracket.
The 2026 NCAA Tournament is underway, with the Sweet 16 stage featuring several exciting matchups. Purdue faces Texas, while Illinois takes on Houston. Texas is the closest Cinderella story left in the tournament, while Houston plays near its campus. Expert Thomas Casale has made his Sweet 16 picks, including No. 1 Michigan handling No. 4 Alabama. Casale has decades of experience and a strong track record of accurate predictions. He is backing a major upset, with a No. 1 seed failing to win its region.
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