Bacterial enzyme found to synthesize DNA using a protein template
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A bacterial enzyme has been discovered that synthesizes DNA using a protein template, challenging the conventional rule that DNA or RNA is required. The finding could lead to new biotechnology tools, similar to CRISPR technology.
A research team at Stanford University has identified a bacterial enzyme that synthesizes DNA using a protein as a template. The enzyme, Drt3b, operates by having amino acids in its active site function like an RNA template to synthesize a DNA strand. This discovery challenges the conventional principle of DNA synthesis, which requires a DNA or RNA strand as a template. The DRT3 defense system, where this enzyme is found, is present in various bacteria, suggesting that this new synthesis method may be common. The research team hopes to use DRT3 as a new biotechnology tool, potentially allowing for the creation of desired base sequences. The discovery has been described as 'groundbreaking' and could lead to further uncovering of biochemical reactions in the microbial world.
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