Buprenorphine in pregnancy better than methadone for infants, similar for kids, studies find
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A study found that infants born to mothers who used buprenorphine during pregnancy had better health outcomes than those exposed to methadone. A follow-up study found similar rates of neurodevelopmental disorders in children exposed to either medication.
Researchers at Harvard University and Stanford Medicine analyzed data from over 31,000 pregnant women with opioid use disorder. Infants exposed to buprenorphine had better health outcomes than those exposed to methadone. A follow-up study found similar rates of neurodevelopmental disorders in children exposed to either medication. The studies used a database of pregnant women enrolled in public insurance programs from 2000 to 2018. The findings suggest that buprenorphine may be a better treatment option for pregnant women with opioid use disorder. More data is needed to inform treatment decisions.
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