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Duke vs. St. John's odds, March Madness predictions: 2026 NCAA Tournament Sweet 16 picks from proven model

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Duke vs. St. John's odds, March Madness predictions: 2026 NCAA Tournament Sweet 16 picks from proven model

The Duke Blue Devils face the St. John's Red Storm in the NCAA Tournament Sweet 16 on Friday. The Blue Devils are 6.5-point favorites, with the over/under for total points scored at 141.5.

The Duke Blue Devils and St. John's Red Storm meet in the NCAA Tournament Sweet 16. Duke is a 6.5-point favorite, with an over/under of 141.5 points. The game is on Friday at 7:10 p.m. ET at Capital One Arena in Washington, D.C. St. John's won its last game 67-65 against Kansas, while Duke defeated TCU 81-58. The Blue Devils have won 13 straight games, while the Red Storm have won eight in a row. Duke's Caleb Foster and Patrick Ngongba are listed as questionable.

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